Blossary – Antihypertensive drugs

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More than one in three adults worldwide have raised blood pressure – a condition that causes around half of all deaths from stroke and heart disease. It is considered directly responsible for 7.5 million deaths in 2004 – almost 13% of all global deaths. In nearly all high-income countries, widespread diagnosis and treatment with low-cost medication have led to a dramatic drop in mean blood pressure across populations – and this has contributed to a reduction in deaths from heart disease.

Category: Health

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Created by: marija.horvat

Number of Blossarys: 21

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benzodiazepine

Although controversial over this off-label purpose, benzodiazepines may play a role in lowering blood pressure. They work as an agonist of the GABA-a receptors in the brain, thus slowing down ...

renin inhibitor

Renin inhibitors produce vasodilation by inhibiting the activity of renin, which is responsible for stimulating angiotensin II formation. Renin is a proteolytic enzyme that is released by the kidneys ...

aldosterone receptor antagonist

Aldosterone receptor antagonists are medicines that help the body get rid of extra water (diuretics). They also have other properties that can prevent heart failure from becoming worse, along with ...

alpha-2 adrenergic receptor agonist

Alpha-adrenoceptor agonists (α-agonists) bind to α-receptors on vascular smooth muscle and induce smooth contraction and vasoconstriction, thus mimicking the effects of sympathetic adrenergic nerve ...

endothelin receptor blocker

Endothelin receptor antagonists, by blocking the vasoconstrictor and cardiotonic effects of ET-1, produce vasodilation and cardiac inhibition. Endothelin receptor antagonists have been shown to ...

hypertension

Hypertension, also referred to as high blood pressure, is a condition in which the arteries have persistently elevated blood pressure. Every time the human heart beats, it pumps blood to the whole ...